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Similar to "An unexpected decryption error occurred", the error 108 can be caused by corrupted, damaged or incomplete installation files.
This can often times be caused by closing the downloader early.
We've recently become aware that playing Diablo III with the latest Catalyst 12.4 drivers for ATI cards may cause some visual artifacts for specific hardware configurations.
This issue affects users of ATI Radeon HD 2400, 2600, 2900, 3400, 36 graphics cards under Windows Vista and Windows 7.
Whether you repair your previous install or download the entire game again, it's necessary to use this new downloader to install and play the game when it launches.